Background Sarcoidosis is a granulomatous disease of unknown etiology. Macrophages
play a key role in granuloma formation with the T cells, having a significant impact on
macrophage polarization (M1 and M2) and the cellular composition of the granuloma. This
study evaluates macrophage polarization in granulomas in pulmonary sarcoidosis. Materials
and Methods Tissue specimens from the Department of Pathology biobank at the Masih
Daneshvari Hospital were obtained. Paraffin sections from 10 sarcoidosis patients were …