Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 …

A Hirata, D Sugiyama, M Watanabe… - Journal of clinical …, 2018 - Elsevier
Background The effect of very high or extremely high levels of high-density lipoprotein
cholesterol (HDL-C) on cardiovascular disease (CVD) is not well described. Although a few
recent studies have reported the adverse effects of extremely high levels of HDL-C on CVD
events, these did not show a statistically significant association between extremely high
levels of HDL-C and cause-specific CVD mortality. In addition, Asian populations have not
been studied. Objective We examine the impact of extremely high levels of HDL-C on cause …