Vascular endothelial cells synthesize a plasma membrane protein indistinguishable from the platelet membrane glycoprotein IIa.
JA van Mourik, OC Leeksma, JH Reinders… - Journal of Biological …, 1985 - ASBMB
To define the role of membrane components that function in endothelial cell physiology and
to characterize them biochemically, we have attempted to prepare monoclonal antibodies
specific for endothelial cells. Several clones were obtained producing antibodies which
bound to endothelial cells and also to platelets. The antibody of one of these clones, CLB-
HEC 75, was studied in more detail. This antibody is directed against a single protein which
is synthesized constitutively by endothelial cells and is expressed on the surface of both …
to characterize them biochemically, we have attempted to prepare monoclonal antibodies
specific for endothelial cells. Several clones were obtained producing antibodies which
bound to endothelial cells and also to platelets. The antibody of one of these clones, CLB-
HEC 75, was studied in more detail. This antibody is directed against a single protein which
is synthesized constitutively by endothelial cells and is expressed on the surface of both …