[HTML][HTML] Neurogastroenterology and Motility: Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve fibers in mouse colorectum

T Guo, S Patel, D Shah, L Chi, S Emadi… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Colorectal hypersensitivity and sensitization of both mechanosensitive and mechanically
insensitive afferents develop after intracolonic instillation of 2, 4, 6-trinitrobenzenesulfonic
acid (TNBS) in the mouse, a model of postinfectious irritable bowel syndrome. In mice in
which∼ 80% of extrinsic colorectal afferents were labeled genetically using the promotor for
vesicular glutamate transporter type 2 (VGLUT2), we systematically quantified the
morphology of VGLUT2-positive axons in mouse colorectum 7–28 days following …

Optical clearing reveals TNBS-induced morphological changes of VGLUT2-positive nerve fibers in mouse colorectum

T Guo, S Patel, D Shah, L Chi… - American Journal …, 2021 - journals.physiology.org
Colorectal hypersensitivity and sensitization of both mechanosensitive and mechanically
insensitive afferents develop after intracolonic instillation of 2, 4, 6-trinitrobenzenesulfonic
acid (TNBS) in the mouse, a model of postinfectious irritable bowel syndrome. In mice in
which∼ 80% of extrinsic colorectal afferents were labeled genetically using the promotor for
vesicular glutamate transporter type 2 (VGLUT2), we systematically quantified the
morphology of VGLUT2-positive axons in mouse colorectum 7–28 days following …