Sex differences in circadian timing systems: implications for disease

M Bailey, R Silver - Frontiers in neuroendocrinology, 2014 - Elsevier
Virtually every eukaryotic cell has an endogenous circadian clock and a biological sex.
These cell-based clocks have been conceptualized as oscillators whose phase can be reset
by internal signals such as hormones, and external cues such as light. The present review
highlights the inter-relationship between circadian clocks and sex differences. In mammals,
the suprachiasmatic nucleus (SCN) serves as a master clock synchronizing the phase of
clocks throughout the body. Gonadal steroid receptors are expressed in almost every site …