[HTML][HTML] Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone …
MOZ (monocytic leukemic zinc-finger protein) and MORF (MOZ-related factor) are histone
acetyltransferases important for HOX gene expression as well as embryo and postnatal
development. They form complexes with other regulatory subunits through the scaffold
proteins BRPF1/2/3 (bromodomain-PHD (plant homeodomain) finger proteins 1, 2, or 3).
BRPF proteins have multiple domains, including two PHD fingers, for potential interactions
with histones. Here we show that the first PHD finger of BRPF2 specifically recognizes the N …
acetyltransferases important for HOX gene expression as well as embryo and postnatal
development. They form complexes with other regulatory subunits through the scaffold
proteins BRPF1/2/3 (bromodomain-PHD (plant homeodomain) finger proteins 1, 2, or 3).
BRPF proteins have multiple domains, including two PHD fingers, for potential interactions
with histones. Here we show that the first PHD finger of BRPF2 specifically recognizes the N …