Antimicrobial peptides in nasal secretion and mucosa with respect to Staphylococcus aureus colonization in chronic rhinosinusitis with nasal polyps.
ML Thienhaus, J Wohlers, R Podschun, J Hedderich… - Rhinology, 2011 - europepmc.org
ML Thienhaus, J Wohlers, R Podschun, J Hedderich, P Ambrosch, M Laudien
Rhinology, 2011•europepmc.orgObjective Nasal carriage of Staphylococcus aureus in patients with chronic rhinosinusitis
with nasal polyps (NP) is hypothesized to have pathophysiological impact on the disease.
Antimicrobial peptides (AMP), especially human beta-defensin-3 (hBD-3) and LL-37, are an
important part of the multifactorial defence against microorganisms in barrier organs like the
nasal mucosa. The interaction of S. aureus colonization and AMP in nasal secretions and
mucosa of NP were investigated in this study.
with nasal polyps (NP) is hypothesized to have pathophysiological impact on the disease.
Antimicrobial peptides (AMP), especially human beta-defensin-3 (hBD-3) and LL-37, are an
important part of the multifactorial defence against microorganisms in barrier organs like the
nasal mucosa. The interaction of S. aureus colonization and AMP in nasal secretions and
mucosa of NP were investigated in this study.
Objective
Nasal carriage of Staphylococcus aureus in patients with chronic rhinosinusitis with nasal polyps (NP) is hypothesized to have pathophysiological impact on the disease. Antimicrobial peptides (AMP), especially human beta-defensin-3 (hBD-3) and LL-37, are an important part of the multifactorial defence against microorganisms in barrier organs like the nasal mucosa. The interaction of S. aureus colonization and AMP in nasal secretions and mucosa of NP were investigated in this study.
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