Study of protective effect on rat cochlear spiral ganglion after blast exposure by adenovirus-mediated human β-nerve growth factor gene
J Wu, B Liu, J Fan, Q Zhu, J Wu - American journal of otolaryngology, 2011 - Elsevier
OBJECTIVE: To study whether adenovirus-mediated human β-nerve growth factor (Ad-
hNGFβ) gene has any protective effect on rat cochlear spiral ganglion after blast exposure.
METHODS: Deafness was induced by blast exposure (172.0 dB) in 20 healthy rats. Seven
days after blast exposure, Ad-hNGFβ was infused into the perilymphatic space of 10 animals
as the hNGFβ/blast group, and artificial perilymph fluid (APF) was infused into the
perilymphatic space of 10 animals as the APF/blast control group. An additional control …
hNGFβ) gene has any protective effect on rat cochlear spiral ganglion after blast exposure.
METHODS: Deafness was induced by blast exposure (172.0 dB) in 20 healthy rats. Seven
days after blast exposure, Ad-hNGFβ was infused into the perilymphatic space of 10 animals
as the hNGFβ/blast group, and artificial perilymph fluid (APF) was infused into the
perilymphatic space of 10 animals as the APF/blast control group. An additional control …