Different expression of androgen receptor coactivators in human prostate

N Fujimoto, A Mizokami, S Harada, T Matsumoto - Urology, 2001 - Elsevier
Objectives. To investigate the expression of androgen receptor (AR) coactivators in the
human prostate for a better understanding of androgen action in prostate cancer. Methods.
Using reverse transcriptase-polymerase chain reaction, we examined the expression levels
of AR coactivators (ARA55, SRC1, ARA54, TIF2, RAC3) in four prostate cancer cell lines
(DU145, PC3, LNCaP, and LN-TR2), nine benign prostatic tissue samples, and 21 prostate
cancer tissue specimens. Results. In the cell lines, SRC1 was expressed ubiquitously at …