[HTML][HTML] Regulation of cardiomyocyte full-length tissue factor expression and microparticle release under inflammatory conditions in vitro
S Antoniak, U Boltzen, A Eisenreich… - Journal of Thrombosis …, 2009 - Elsevier
Background: Myocardial inflammation is associated with an increase in circulating
microparticles (MPs) and procoagulability. Objectives: We determined whether acute
inflammation was associated with altered full-length tissue factor (flTF) expression and
increased procoagulability in cardiomyocytic cells. Methods: This study examined the
transcriptional regulation of flTF expression in murine cardiomyocytic (HL-1) cells. Also, the
generation of MPs by HL-1 cells and their ability to diffuse through an artificial endothelium …
microparticles (MPs) and procoagulability. Objectives: We determined whether acute
inflammation was associated with altered full-length tissue factor (flTF) expression and
increased procoagulability in cardiomyocytic cells. Methods: This study examined the
transcriptional regulation of flTF expression in murine cardiomyocytic (HL-1) cells. Also, the
generation of MPs by HL-1 cells and their ability to diffuse through an artificial endothelium …