Effect of high-fat diet on sarcoplasmic reticulum Ca (++)-ATPase activity in different types of rat skeletal muscle.
L Aagaard, A Nawrocki, K Madsen - Roczniki Akademii Medycznej w …, 2002 - europepmc.org
L Aagaard, A Nawrocki, K Madsen
Roczniki Akademii Medycznej w Bialymstoku (1995), 2002•europepmc.orgThe aim of the present study was to examine the effect of a high-fat diet on the Ca (2+)-
ATPase activity in the sarcoplasmic reticulum of the flexor digitorum longus (fast-twitch,
glycolytic muscle) and the soleus (slow-twitch, oxidative muscle). The enzyme activity in the
extensor digitorum longus was several-fold higher than in the soleus. The high-fat diet
increased the enzyme activity by 22%(p< 0.05) in the soleus but it had no effect in the flexor
digitorum longus. It is concluded that a high-fat diet increases the activity of only one isoform …
ATPase activity in the sarcoplasmic reticulum of the flexor digitorum longus (fast-twitch,
glycolytic muscle) and the soleus (slow-twitch, oxidative muscle). The enzyme activity in the
extensor digitorum longus was several-fold higher than in the soleus. The high-fat diet
increased the enzyme activity by 22%(p< 0.05) in the soleus but it had no effect in the flexor
digitorum longus. It is concluded that a high-fat diet increases the activity of only one isoform …
The aim of the present study was to examine the effect of a high-fat diet on the Ca (2+)-ATPase activity in the sarcoplasmic reticulum of the flexor digitorum longus (fast-twitch, glycolytic muscle) and the soleus (slow-twitch, oxidative muscle). The enzyme activity in the extensor digitorum longus was several-fold higher than in the soleus. The high-fat diet increased the enzyme activity by 22%(p< 0.05) in the soleus but it had no effect in the flexor digitorum longus. It is concluded that a high-fat diet increases the activity of only one isoform of the enzyme, namely the one which is present in the slow-twitch oxidative fibers.
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