[HTML][HTML] Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway: a role for mixed …

H Teramoto, OA Coso, H Miyata, T Igishi, T Miki… - Journal of Biological …, 1996 - ASBMB
Certain small GTP-binding proteins control the enzymatic activity of a family of closely
related serine-threonine kinases known as mitogen-activated protein kinases (MAPKs). In
turn, these MAPKs, such as p44 mapk and p42 mapk, referred to herein as MAPKs, and
stress-activated protein kinases, also termed c-Jun N-terminal kinases (JNKs),
phosphorylate and regulate the activity of key molecules that ultimately control the
expression of genes essential for many cellular processes. Whereas Ras controls the …