Stem cell factor influences neuro-immune interactions: the response of mast cells to pituitary adenylate cyclase activating polypeptide is altered by stem cell factor
A Schmidt-Choudhury, J Meißner, J Seebeck… - Regulatory peptides, 1999 - Elsevier
Mast cells degranulation can be elicited by a number of biologically important
neuropeptides, but the mechanisms involved in mast cell–neuropeptide interactions have
not been fully elucidated. Stem cell factor (SCF), also known as c-kit or kit ligand, induces
multiple effects on mast cells, including proliferation, differentiation, maturation, and prevents
apoptosis. We investigated the ability of SCF to affect mast cell responsiveness to the
neuropeptides pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive …
neuropeptides, but the mechanisms involved in mast cell–neuropeptide interactions have
not been fully elucidated. Stem cell factor (SCF), also known as c-kit or kit ligand, induces
multiple effects on mast cells, including proliferation, differentiation, maturation, and prevents
apoptosis. We investigated the ability of SCF to affect mast cell responsiveness to the
neuropeptides pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive …
