Mouse oncogene protein 24p3 is a member of the lipocalin protein family
DR Flower, ACT North, TK Attwood - Biochemical and biophysical research …, 1991 - Elsevier
DR Flower, ACT North, TK Attwood
Biochemical and biophysical research communications, 1991•ElsevierRigorous new methods of protein sequence analysis have been applied to the lipocalins, a
diverse family of ligand binding proteins. Using three conserved sequence motifs to search
for similar patterns in a large sequence database, the size and composition of this protein
family have been defined in an automatic and objective way. It has allowed the identification
of an existing sequence, mouse 24p3 protein, as a lipocalin and the possible rejection of
other putative members from this protein family. On the basis of this newly discovered …
diverse family of ligand binding proteins. Using three conserved sequence motifs to search
for similar patterns in a large sequence database, the size and composition of this protein
family have been defined in an automatic and objective way. It has allowed the identification
of an existing sequence, mouse 24p3 protein, as a lipocalin and the possible rejection of
other putative members from this protein family. On the basis of this newly discovered …
Summary
Rigorous new methods of protein sequence analysis have been applied to the lipocalins, a diverse family of ligand binding proteins. Using three conserved sequence motifs to search for similar patterns in a large sequence database, the size and composition of this protein family have been defined in an automatic and objective way. It has allowed the identification of an existing sequence, mouse 24p3 protein, as a lipocalin and the possible rejection of other putative members from this protein family. On the basis of this newly discovered homology, a possible function for mouse 24p3 protein is proposed.
Elsevier