Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate.
F Gaspari, N Perico, P Ruggenenti… - Journal of the …, 1995 - journals.lww.com
Renal clearance of inulin is the best available indicator of GFR but cannot be used routinely
for clinical purposes and is also difficult to perform for clinical investigation when repeated
measurements are required. The aim of this study was to find a reliable alternative to inulin
clearance that would allow one to avoid the use of radioactivity and problems related to the
continuous infusion of the marker. The plasma clearance of unlabeled iohexol, a nonionic
contrast agent, was used. Forty-one patients (creatinine clearance 6 to 160 mL/min per 1.73 …
for clinical purposes and is also difficult to perform for clinical investigation when repeated
measurements are required. The aim of this study was to find a reliable alternative to inulin
clearance that would allow one to avoid the use of radioactivity and problems related to the
continuous infusion of the marker. The plasma clearance of unlabeled iohexol, a nonionic
contrast agent, was used. Forty-one patients (creatinine clearance 6 to 160 mL/min per 1.73 …