Assessment of risk of overt nephropathy in diabetic patients from albumin excretion in untimed urine specimens
RG Nelson, WC Knowler, DJ Pettitt… - Archives of internal …, 1991 - jamanetwork.com
The ability of an albumin-to-creatinine ratio, measured in a single untimed urine specimen,
to indicate the likelihood of developing overt diabetic nephropathy was determined in 439
Pima Indians (134 men, 305 women) aged 25 years or older with non—insulin-dependent
diabetes. During a mean follow-up period of 4.2 years, 59 (13%) of the subjects developed
overt nephropathy, 47 (80%) of whom had albumin-to-creatinine ratios of 30 mg/g or greater
at baseline. Subjects with albumin-to-creatinine ratios of 30 to 299 mg/g (a level of excretion …
to indicate the likelihood of developing overt diabetic nephropathy was determined in 439
Pima Indians (134 men, 305 women) aged 25 years or older with non—insulin-dependent
diabetes. During a mean follow-up period of 4.2 years, 59 (13%) of the subjects developed
overt nephropathy, 47 (80%) of whom had albumin-to-creatinine ratios of 30 mg/g or greater
at baseline. Subjects with albumin-to-creatinine ratios of 30 to 299 mg/g (a level of excretion …