The renal glomerulus, whose cellular components are developmentally derived from the
mesenchyme, plays a pivotal role in filtratating plasma. Irretrievable changes of glomerular
components are responsible for the initiation and progression of impaired renal function.
Recently, it has been shown that functional stem cells exist in the bone marrow of adult
bodies and that they can reconstitute damaged tissues of the mesenchymal origin. To
examine whether the bone marrow provides stem cells to damaged glomeruli, transgenic …