Promises and pitfalls in the reconstitution of immunity in patients who have HIV-1 infection

RT Gandhi, BD Walker - Current opinion in immunology, 2002 - Elsevier
RT Gandhi, BD Walker
Current opinion in immunology, 2002Elsevier
Recent studies suggest that immunologic containment of HIV-1 is possible and the immune
correlates of this control are being defined. There have been significant advances in our
ability to elicit virus-specific immune responses, which have led to viral control in animal
models. Although viral escape from the immune system is an important challenge, new
strategies for therapeutic and preventative HIV-1 vaccination are being vigorously pursued
in human trials.
Recent studies suggest that immunologic containment of HIV-1 is possible and the immune correlates of this control are being defined. There have been significant advances in our ability to elicit virus-specific immune responses, which have led to viral control in animal models. Although viral escape from the immune system is an important challenge, new strategies for therapeutic and preventative HIV-1 vaccination are being vigorously pursued in human trials.
Elsevier