The differential expression of VEGF, VEGFR-2, and GLUT-1 proteins in disease subtypes of systemic sclerosis
CA Davies, M Jeziorska, AJ Freemont, AL Herrick - Human pathology, 2006 - Elsevier
Our aim was to evaluate (a) whether there is differential expression of the endothelial
regulator vascular endothelial growth factor (VEGF), its receptor (VEGFR-2), and the hypoxia-
associated glucose transporter molecule, GLUT-1, in skin biopsies from different disease
subtypes of systemic sclerosis (SSc) and (b) whether they associate with dermal calcinosis,
a significant complication of SSc. Skin punch biopsies were taken from the forearms of 66
SSc patients including 18 with limited cutaneous disease without calcinosis (lcSSc), 23 with …
regulator vascular endothelial growth factor (VEGF), its receptor (VEGFR-2), and the hypoxia-
associated glucose transporter molecule, GLUT-1, in skin biopsies from different disease
subtypes of systemic sclerosis (SSc) and (b) whether they associate with dermal calcinosis,
a significant complication of SSc. Skin punch biopsies were taken from the forearms of 66
SSc patients including 18 with limited cutaneous disease without calcinosis (lcSSc), 23 with …