Intravenous ribavirin is a safe and cost-effective treatment for respiratory syncytial virus infection after lung transplantation

AR Glanville, AIR Scott, JM Morton, CL Aboyoun… - The Journal of heart and …, 2005 - Elsevier
BACKGROUND: Community-acquired viral infections, such as respiratory syncytial virus
(RSV), represent a risk factor for bronchiolitis obliterans syndrome (BOS), the major limiting
factor for long-term survival after lung transplantation (LTx). RSV often presents with acute
bronchiolitis and may be fatal in 10% to 20% of patients. Standard therapies for RSV include
nebulized ribavirin with or without steroids, but are costly and inconvenient. We investigated
the utility of intravenous (IV) ribavirin with steroids for the treatment of RSV infection after …