Bcl-x exists in two isoforms, the anti-apoptotic form Bcl-xL and the proapoptotic form Bcl-xS.
The critical balance between the two forms appears to be important for cell survival;
however, it is still not clear exactly how the vital balance is maintained. Using an in vitro
spermatogenic cell apoptosis model, this study provides a new insight into the possible role
of Ca 2+ in regulating the Bcl-xS and Bcl-xL expression. 2, 5-Hexanedione, a metabolite of
the common industrial solvent n-hexane, caused a significant increase in reactive oxygen …