Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody
M Takeya, T Yoshimura, EJ Leonard, K Takahashi - Human pathology, 1993 - Elsevier
The infiltration of blood monocytes into the subendothelial space is thought to be one of the
most important pathologic events in early atherogenesis. To examine the mechanism of
monocyte migration in early atherosclerotic lesions we investigated immunohistochemically
the production of monocyte chemoattractant protein-1 (MCP-1) in various atherosclerotic
lesions, including diffuse intimal thickening, fatty streaks, and atheromatous plaques,
obtained during autopsies of patients of various ages. A highly specific anti-MCP-1 …
most important pathologic events in early atherogenesis. To examine the mechanism of
monocyte migration in early atherosclerotic lesions we investigated immunohistochemically
the production of monocyte chemoattractant protein-1 (MCP-1) in various atherosclerotic
lesions, including diffuse intimal thickening, fatty streaks, and atheromatous plaques,
obtained during autopsies of patients of various ages. A highly specific anti-MCP-1 …
