Identification, Characterization, Cloning, and Expression of Apolipoprotein C-IV, a Novel Sialoglycoprotein of Rabbit Plasma Lipoproteins (∗)
LH Zhang, L Kotite, RJ Havel - Journal of Biological Chemistry, 1996 - ASBMB
We have identified and characterized a novel proline-and arginine-rich protein component
of lipoproteins, present in up to five sialylated isoforms, in rabbit blood plasma. The pI of the
desialylated protein is 5.7. Based upon its N-terminal sequence, a complete cDNA
sequence of 555 nucleotides was cloned from rabbit liver. The synthesized protein is
predicted to contain 124 amino acids, including a typical signal peptide of 27 residues. The
mature protein of 97 amino acids, designated apolipoprotein C-IV, is associated with the …
of lipoproteins, present in up to five sialylated isoforms, in rabbit blood plasma. The pI of the
desialylated protein is 5.7. Based upon its N-terminal sequence, a complete cDNA
sequence of 555 nucleotides was cloned from rabbit liver. The synthesized protein is
predicted to contain 124 amino acids, including a typical signal peptide of 27 residues. The
mature protein of 97 amino acids, designated apolipoprotein C-IV, is associated with the …
