[PDF][PDF] The use of human skin for the detection of antiepithelial autoantibodies
SI Katz, K Halprin, TM Inderbitzin - J Invest Derm, 1969 - core.ac.uk
SI Katz, K Halprin, TM Inderbitzin
J Invest Derm, 1969•core.ac.ukHuman skin as test substrate in the indirect immunofluorescent test has been found to be
superior to rabbit esophagus in that it is considerably more sensitive for the detection of
antiepithelial antibodies. By using horizontal skin sections rather than conventional vertical
sections, the accuracy and reliability of the test has been greatly enhanced. The test
technique which we describe is simple to perform, and yields re-producible results. There
was a good correlation between the initial serum antiepithelial antibody titer and the activity …
superior to rabbit esophagus in that it is considerably more sensitive for the detection of
antiepithelial antibodies. By using horizontal skin sections rather than conventional vertical
sections, the accuracy and reliability of the test has been greatly enhanced. The test
technique which we describe is simple to perform, and yields re-producible results. There
was a good correlation between the initial serum antiepithelial antibody titer and the activity …
Abstract
Human skin as test substrate in the indirect immunofluorescent test has been found to be superior to rabbit esophagus in that it is considerably more sensitive for the detection of antiepithelial antibodies. By using horizontal skin sections rather than conventional vertical sections, the accuracy and reliability of the test has been greatly enhanced. The test technique which we describe is simple to perform, and yields re-producible results.
There was a good correlation between the initial serum antiepithelial antibody titer and the activity of disease in patients with pemphigus and bullous pemphigoid. In following the course of the disease in five patients the activity of the skin affection was usually reflected by the serum antibody levels.
core.ac.uk
