Osteogenic stem cells and the stromal system of bone and marrow

JN Beresford - Clinical Orthopaedics and Related Research®, 1989 - journals.lww.com
According to current hypothesis, cells of the osteogenic lineage, which includes both
osteoblasts and chondroblasts, are derived from a stromal stem cell in the postnatal
organism. That there exist osteogenic precursors in association with the soft, fibrous tissue of
the marrow stroma is well established. An osteogenic tissue comprised of cartilage and
bone is formed when marrow or marrow cell suspensions are cultured in vivo within diffusion
chambers. Bone with a functional marrow organ is formed when marrow or marrow cell …