Development of the mammalian enteric nervous system

S Taraviras, V Pachnis - Current opinion in genetics & development, 1999 - Elsevier
S Taraviras, V Pachnis
Current opinion in genetics & development, 1999Elsevier
The mammalian enteric nervous system is derived from neural crest cells which invade the
foregut and hindgut mesenchyme. It has been established that signalling molecules
produced by the mesenchyme of the gut wall play a critical role in the development of the
mammalian enteric nervous system. Recent studies have characterised further the role of
such molecules and have identified novel extracellular and intracellular signals that are
critical for enteric ganglia formation.
The mammalian enteric nervous system is derived from neural crest cells which invade the foregut and hindgut mesenchyme. It has been established that signalling molecules produced by the mesenchyme of the gut wall play a critical role in the development of the mammalian enteric nervous system. Recent studies have characterised further the role of such molecules and have identified novel extracellular and intracellular signals that are critical for enteric ganglia formation.
Elsevier