Quantification of the Contribution of Extracellular Sodium to23Na Multiple-Quantum-Filtered NMR Spectra of Suspensions of Human Red Blood Cells
T Knubovets, H Shinar, G Navon - Journal of Magnetic Resonance, 1998 - Elsevier
23Na double-quantum-filtered (DQF) NMR enables the detection of anisotropic motion of
sodium ions due to their interaction with ordered structures in biological tissues. Using the
technique, anisotropic motion was found for sodium ions in mammalian red blood cell
suspensions (RBC) and the effect was shown to correlate with the integrity of membrane
cytoskeleton. In the present study relative contributions to the DQF and triple-quantum-
filtered (TQF) spectra of sodium bound to anisotropic and isotropic binding sites in the intra …
sodium ions due to their interaction with ordered structures in biological tissues. Using the
technique, anisotropic motion was found for sodium ions in mammalian red blood cell
suspensions (RBC) and the effect was shown to correlate with the integrity of membrane
cytoskeleton. In the present study relative contributions to the DQF and triple-quantum-
filtered (TQF) spectra of sodium bound to anisotropic and isotropic binding sites in the intra …
