Streptococcal pyrogenic exotoxin A (SPE A) superantigen induced production of hematopoietic cytokines, IL-12 and IL-13 by human peripheral blood mononuclear …

H Müller-Alouf, D Gerlach, P Desreumaux… - Microbial …, 1997 - Elsevier
A quantitative and kinetic study of the release of the hematopoietic cytokines IL-3, IL-5 and
GM-CSF, the immunoregulatory cytokine IL-12 heterodimer (and its p40 subunit) and IL-13
by human peripheral blood mononuclear cells (PBMC) stimulatedin vitrowith the
superantigen streptococcal pyrogenic (erythrogenic) exotoxin A (SPE A) fromStreptococcus
pyogenesis reported. PBMC were stimulated in parallel with heat-killed group A
streptococcal cells, E. colilipopolysaccharide (LPS) and with concanavalin A (Con A) in …