[HTML][HTML] The relationship between serum IgE and surface levels of FcϵR on human leukocytes in various diseases: correlation of expression with FcϵRI on basophils …
Background: Expression of receptors for IgE (FcϵR) have been mainly studied on mast cells
and blood basophils in the context of allergic disease. Some reports have noted limited
expression of FcϵR on other leukocytes, including blood monocytes and eosinophils in
certain patients. An association between human blood basophil expression of FcϵRIα and
serum IgE has been noted among allergic subjects. Objective: Recent evidence supports
regulation of FcϵRIα by free IgE on both mast cells and basophils. We hypothesized that this …
and blood basophils in the context of allergic disease. Some reports have noted limited
expression of FcϵR on other leukocytes, including blood monocytes and eosinophils in
certain patients. An association between human blood basophil expression of FcϵRIα and
serum IgE has been noted among allergic subjects. Objective: Recent evidence supports
regulation of FcϵRIα by free IgE on both mast cells and basophils. We hypothesized that this …
