Mechanism of lipolysis induced by electrical stimulation of the hypothalamus in the rabbit
A Kumon, A Takahashi, T Hara, T Shimazu - Journal of Lipid Research, 1976 - ASBMB
Electrical stimulation of the ventro-medial hypothalamus of the rabbit elevated plasma
glycerol concentration. This elevation was suppressed by treatments of the animals with
hexamethonium and propranolol, or by adrenalectomy, but was not suppressed by
treatments with atropine and phentolamine. These results would indicate that the effect of
electrical stimulation of ventro-medial hypothalamus is mainly mediated by catecholamine
(s) liberated from the adrenal medulla and acts on β-receptor of adipose tissue.
glycerol concentration. This elevation was suppressed by treatments of the animals with
hexamethonium and propranolol, or by adrenalectomy, but was not suppressed by
treatments with atropine and phentolamine. These results would indicate that the effect of
electrical stimulation of ventro-medial hypothalamus is mainly mediated by catecholamine
(s) liberated from the adrenal medulla and acts on β-receptor of adipose tissue.
